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Clinical, radiographic and histologic evaluation of cystic oral lesions in cats


The purpose of this case series was to assess correlations between clinical and radiographic findings, histopathologic interpretation and signalment to identify common characteristics and provide recommendations for clinicians and pathologists to optimize diagnostic efficiency and accuracy for cystic oral lesions in cats.  

Feline cystic oral lesions are uncommon and include odontogenic cysts and cystic odontogenic tumors. Accurate diagnosis requires close collaboration between the clinician's clinical and radiographic findings and the pathologist's histologic interpretations.  

The odontogenic cysts identified in this series include a periapical cyst, dentigerous cysts and a type of unclassified collateral cyst (UCC) that appears to be a previously undefined, distinct entity in cats.  

Many of the cysts (52%) were unable to be classified due to insufficient diagnostic information, which often related to the associated tooth being unavailable for evaluation.  

Cystic odontogenic tumors included ameloblastomas, amyloid producing ameloblastomas (APA), and feline inductive odontogenic tumors (FIOT).  

Clinical, Radiographic and Histologic Evaluation of 40 Cystic Oral Lesions in 37 Cats.” Daniel J Clayton, et al. J Vet Dent. 2022 Aug 9;8987564221119956. doi: 10.1177/08987564221119956. 

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