MY ACCOUNT | NEWSLETTER |

Next-generation DNA sequencing will help detect bovine diseases earlier

The research project that develops this technique will focus on the viruses responsible for foot-and-mouth disease and those that belong to the complex of bovine respiratory diseases.


A group of researchers from the Cornell University Animal Health Diagnostic Center and the Texas A&M Veterinary Medical Diagnostic Laboratory is developing a project that aims to mitigate the risks that certain diseases pose to the livestock industry through the development of technology to detect them before they appear or become outbreaks.

The project, which will receive funding of one million dollars from the National Institute of Food and Agriculture of the US Department of Agriculture, will be launched in collaboration with the National Network of Animal Health Laboratories and the Center of Plum Island Animal Diseases.

Against foot-and-mouth disease and respiratory diseases

The aim of the project is to develop new methods for the early detection of transboundary and emerging diseases within the livestock industry using next-generation DNA sequencing. The research will focus on the viruses responsible for foot-and-mouth disease and those belonging to the complex of bovine respiratory diseases: bovine viral diarrhea virus, bovine coronavirus, bovine respiratory syncytial virus, and bovine parainfluenza virus type 3.

During the first two years of this project, the research team will develop and optimize targeted and randomized next-generation sequencing diagnostic workflows for the early detection and characterization of current, transboundary, and emerging pathogens in livestock.

In the next phase, highly specialized bioinformaticians will develop rapid and semi-automated tools for data analysis. The third and last year of the project will consist of instructing the laboratories of the National Network of Animal Health Laboratories in the sequencing procedures and processes that the team will develop.

High-throughput DNA sequencing

Next-generation sequencing encompasses the use of modern high-throughput DNA sequencing methods. These methods allow faster and more cost-effective detection of DNA and RNA in biological samples and the characterization of pathogens.

Currently, real-time polymerase chain reaction (rtPCR) assays are used more widely in diagnostic laboratories for the rapid detection of pathogens. These assays are useful but are based on existing genomic information and may not detect emerging pathogens or variants of known pathogens.

Furthermore, rtPCR assays do not provide the specific genomic information necessary to trace the source of disease outbreaks and differentiate strains, critical information necessary to develop corrective epidemiological actions.

The widespread application of next-generation sequencing technology in diagnostic laboratories has not become widespread due to the lack of standardized protocols and procedures and the need for highly specialized methods to analyze biological data and the scarcity of preparation in this type of sequencing. for diagnostic purposes.

Like0
Dislike0
  • Please enter a comment


Name *
Email address *
Comment *


* Required fields

Information on the processing of your personal data
We inform you that, in compliance with the provisions of current national and European regulations for the Protection of Personal Data and Services of the Information Society and Electronic Commerce, by sending us this form you are expressly giving your consent to Grupo Asís Biomedia , SL, (hereinafter, "ASIS GROUP") so that, as the person in charge, it may process your personal data in order to respond to your request for contact and information by electronic means.

Likewise, when you expressly consent, we will process your personal data to send you specialized information, newsletters, offers and exclusive promotions from GRUPO ASIS and related companies.

For the aforementioned purpose, GRUPO ASIS may transfer your data to other companies linked to GRUPO ASIS or to third party service providers for the management of electronic communications and other security services, even in cases where they are outside of the European Union, provided that they legally guarantee the adequate level of protection required by European regulations.

At any time you can withdraw the consent given and exercise the rights of access, rectification, deletion, portability of your data and limitation or opposition to its treatment by contacting GRUPO ASIS by sending an email to protecciondatos @ grupoasis.com, or by written communication to address at Centro Empresarial El Trovador, 8th floor, office I, Plaza Antonio Beltrán Martínez 1, 50002, Zaragoza (Spain), indicating in either case the Ref. Personal data and the right you exercise, as well as attaching a copy of your ID or replacement identification document.


I have read and accept the treatment of my data according to the informed purpose and according Legal notes and the Privacy Policy
I wish to receive commercial information from GRUPO ASIS and related companies



More news

World Veterinary Dermatology Day

Like0
Dislike0

Artificial insemination market to grow to $3B by 2028

Like0
Dislike0

February is National Pet Dental Health Month

Like0
Dislike0

Falling markets? Don't panic, it's not the first time

Like0
Dislike0

Treatment of canine chronic cutaneous lupus erythematosus with oclacitinib

Like0
Dislike0

Newsletter

 
 

News of interest

EVENTS

Copyright © 2023 - All Rights Reserved
ISSN 2768-198X

Top