Study: Novel intra-articular therapy effectively treats osteoarthritis in dogs

A new treatment is significantly more effective in improving symptoms of moderate to severe hip osteoarthritis in dogs than glucocorticoid alone, according to a study published in "Advances in Diagnostic and Treatment Methods for Joint Diseases in Dogs and Cats," a special issue published by the veterinary journal Animals.

Trial results show that one intra-articular shot of autologous conditioned serum (ACS) improves the overall health of dogs with osteoarthritis and that the combination of ACS with the glucocorticoid triamcinolone led to even faster and longer-lasting improvements in function and pain. 

Adult dogs with osteoarthritis in their hips suffer severe pain and limited movement, lowering their quality of life, according to a news release.

The study compared treatment with ACS alone, treatment with glucocorticoids alone and treatment with Orthogen AG's patented therapy of concomitant ACS and glucocorticoids.

ACS contains the entire blood cell secretome (BCS) after extended coagulation in a defined environment. It contains anti-inflammatory and anabolic proteins derived from the dog's own blood and is processed using Orthogen Veterinary's newly developed proprietary device.

Dr. Joao Alves, a veterinarian and the study's lead author, said in the news release that Orthogen's approach was a very effective treatment, with surprisingly sustainable results. Alves is a police captain who specializes in intra-articular treatments for osteoarthritis in highly trained police working dogs.

Dr. Julien Troillet, a veterinarian and managing director of Orthogen Veterinary GmbH, said the company is seeking global partners to make regenerative medicine broadly available to canine patients.

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