Feline injection site sarcomas
Drs. Mattie Hendrick and Michael Goldschmidt and their colleagues at the Laboratory of Pathology of the University of Pennsylvania School of Veterinary Medicine deserve credit for initially recognizing the increasing incidence of both reactions at the sites of rabies vaccinations and the formation of sarcomas at sites commonly used for injection and vaccination in cats.
Their letter to the editor in the Journal of the American Veterinary Medical Association in October 1991 alerted the profession to “the possibility that fibrosarcomas may arise at injection sites in cats.
” They suggested that this change was related to the enactment of a state law in Pennsylvania requiring the rabies vaccination of cats, and they tracked an increase in tumors arising at common vaccination sites (interscapular region) versus tumors arising at nonvaccination sites (eg, head).
Theirs was the initial histopathologic description of the fibrosarcomas as tumors with a marked inflammatory component, including macrophages containing a gray-brown foreign substance.
Author: Marlene Hauck
Source: https://www.vetsmall.theclinics.com/
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