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Temporal lobe epilepsy in cats


In recent years there has been increased attention to the proposed entity of feline temporal lobe epilepsy (TLE). Epileptic discharges in certain parts of the temporal lobe elicit similar semiology, which justifies grouping these epilepsies under one name. Furthermore, feline TLE patients tend to have histopathological changes within the temporal lobe, usually in the hippocampus.

The initial etiology is likely to be different but may result in hippocampal necrosis and later hippocampal sclerosis. The aim of this article was not only to summarize the clinical features and the possible etiology, but also being work to place TLE within the veterinary epilepsy classification. 

Epilepsies in cats, similar to dogs, are classified based on the etiology into idiopathic epilepsy, structural epilepsy and unknown cause.

TLE seems to be outside of this classification, as it is not an aetiologic category, but a syndrome, associated with a topographic affiliation to a certain anatomical brain structure. Magnetic resonance imaging, histopathologic aspects and current medical therapeutic considerations will be summarized, and emerging surgical options are discussed.

Akos Pakozdy, et al. “Temporal lobe epilepsy in cats.” Vet J. 2023 Jan; 291:105941. doi: 10.1016/j.tvjl.2022.105941.

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