A multiple-session mesotherapy protocol for the management of hip osteoarthritis in police working dogs
Objective: To describe the effect of a mesotherapy protocol in dogs with osteoarthritis.
Animals: 30 dogs.
Procedures: Researchers randomly assigned dogs to a control (CG; n = 10) or a mesotherapy group (MG; 20). CG received meloxicam for 70 days. MG was treated with a combination of lidocaine, piroxicam, and thiocolchicoside, injected in intradermal points.
Clinicians conducted seven treatment sessions. Response to treatment was measured with different instruments: the Canine Brief Pain Inventory, Liverpool Osteoarthritis in Dogs (LOAD) and Canine Orthopedic Index at time 0 (T0), +15 days, +30 days, +60 days, and +90 days after T0. At each time point, the results of the two groups with each instrument were analyzed with the Wilcoxon signed ranks test, P < .05. Kaplan-Meier estimators were compared with the Breslow test.
Results: Dogs had a mean age of 6.9 ± 2.7 years and a body weight of 31.0 ± 6.4 kg. Hip osteoarthritis was classified as mild (n = 9), moderate (17), or severe (4). No differences were found at T0.
Clinicians observed better results in MG at +15 days, +30 days, +60 days and +90 days. Kaplan-Meier estimators showed MG had longer periods with better results than CG in various scores.
Clinical relevance: This mesotherapy protocol reduced pain scores and other clinical metrology instrument scores lasting for longer periods.
João C Alves, Ana Santos, Patrícia Jorge, P Lafuente. "A multiple-session mesotherapy protocol for the management of hip osteoarthritis in police working dogs." American Journal of Veterinary Research. 16 November 2022. DOI: https://doi.org/10.2460/ajvr.22.08.0132
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