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Complete blood count and biochemistry reference intervals for healthy adult sheep in the northeastern United States


To establish ovine CBC and biochemistry reference intervals by sampling 120 healthy adult sheep

Background: Reference intervals (RIs) for routine clinicopathologic data in sheep are sparse. The authors sought to establish hematologic and biochemical RIs from a varied ovine population to improve data interpretation for small ruminant veterinarians.

Objectives: The goal of this study was to establish ovine CBC and biochemistry reference intervals by sampling 120 healthy adult sheep, both male and female, from a variety of breeds, located in the Northeastern United States.

Methods: One hundred and eighteen sheep were included in the CBC RI and 121 sheep were included in the biochemistry panel RI.

Results: RIs for 42 CBC and biochemistry analytes were established in accordance with the American Society for Veterinary Clinical Pathology and Clinical Laboratory Standards Institute guidelines.

Conclusions: These RIs are provided to assist small ruminant veterinarians with the interpretation of CBC and biochemistry panel results in sheep.


“Complete blood count and biochemistry reference intervals for healthy adult sheep in the northeastern United States” Elisha A Frye, et al. Vet Clin Pathol. 2022 Feb 27. doi: 10.1111/vcp.13059.

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