When are gastro-protectors really needed?
Report by Prof. Paolo Silvestrini at the SCIVAC RIMINI 2022 congress held on May 27-29 at the Rimini conference center.
The stomach accumulates, crushes, and slowly pushes the partially digested food into the proximal intestine, where the digestive process and the absorption of nutritional principles continue. The stomach has an important secretory action and controls appetite and satiety. Gastric pH in healthy dogs remains <2 for> 85% of 24 hours, and similar values are reported in cats. However, dogs have a lower basal acid secretory activity than humans, but the peak in response to stimulation is much greater. Consequently, the buffering effect exerted by food that is observed in humans after meals is much less marked in dogs and probably also in cats. The gastroprotective drugs generally used in dogs and cats include the following categories: 1) antacids; 2) antagonists of type 2 histaminergic receptors; 3) proton pump inhibitors; 4) misoprostol; 5) sucralfate.
Situations in which to use gastroprotectors: what is the evidence in dogs and cats? During the talk, Prof. Silvestrini shared his personal experience and illustrated the current scientific evidence on the use of gastroprotectors in pathological conditions such as gastro-duodenal erosion and ulcer, reflux esophagitis, Helicobacter gastritis, damage to the gastric mucosa. Stress-induced liver disease, pancreatitis, kidney disease, and thrombocytopenic bleeding.
"When are gastroprotectors really needed?" Paolo Silvestrini. Congress Proceedings. SCIVAC RIMINI 2022 Congress. Rimini, 27-29 May 2022.
Comments
Copyright © 2025 - All Rights Reserved
ISSN 2768-198X
List
Add
Please enter a comment