Articles Companion animals

04 August 2026

A retrospective (2020-2025), multicenter study of myxomatous mitral valve disease in Chihuahuas from Italy, Sweden, and the United States of America.

Clinical evidence update from Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology

Clinical Context

Peer-reviewed veterinary literature continues to shape everyday decision-making for canine patients, especially when new evidence clarifies diagnosis, treatment selection, monitoring, or clinical outcomes.

What the Study Evaluated

A study published in Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology in 2026 evaluated a retrospective (2020-2025), multicenter study of myxomatous mitral valve disease in Chihuahuas from Italy, Sweden, and the United States of America..

Key Findings

Chihuahuas are affected by myxomatous mitral valve disease (MMVD). The aim of this study was to investigate MMVD in Chihuahuas, specifically clinical and echocardiographic characteristics including probability of pulmonary hypertension (PH), disease progression, and survival. A retrospective study of privately owned Chihuahuas with an echocardiographic study compatible with MMVD from four cardiology centers across three countries (2020-2025) was conducted. Differences between signalment, centers, and American College of Veterinary Internal Medicine (ACVIM) stages were assessed; disease progression and survival analysis were calculated. In...

Why It Matters for Veterinary Professionals

For veterinary professionals, the practical value of this work lies in how the findings may support more structured clinical assessment, clearer monitoring, and more informed decisions for canine patients.

Practical Interpretation

The results should be interpreted in the context of the study design, population, inclusion criteria, and clinical setting. Application in practice should consider patient-specific risk factors, available diagnostics, local standards of care, and clinician judgment.

Clinical Takeaway

Overall, the study adds useful evidence for clinicians seeking to align daily practice with current veterinary research while maintaining a balanced, case-by-case approach.

Read the full article here.

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A retrospective (2020-2025), multicenter study of myxomatous mitral valve disease in Chihuahuas from Italy, Sweden, and the United States of America.

Clinical evidence update from Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology

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