Articles Companion animals

22 July 2026

The combination of lomustine and corticosteroids is a valid chemotherapeutic option in cats with presumptive central nervous system lymphoma.

Clinical evidence update from Journal of the American Veterinary Medical Association

Clinical Context

Peer-reviewed veterinary literature continues to shape everyday decision-making for feline patients, especially when new evidence clarifies diagnosis, treatment selection, monitoring, or clinical outcomes.

What the Study Evaluated

A study published in Journal of the American Veterinary Medical Association in 2026 evaluated the combination of lomustine and corticosteroids is a valid chemotherapeutic option in cats with presumptive central nervous system lymphoma..

Key Findings

To describe the clinical outcomes of 10 cats diagnosed with CNS lymphoma treated with lomustine and corticosteroids. Clinical records of privately owned cats diagnosed with CNS lymphoma and presented to a neurological veterinary center were reviewed. Inclusion criteria were MRI, CSF analysis, treatment with corticosteroids and lomustine, and availability of detailed follow-up data. Cats with incomplete data, alternative diagnoses, or concomitant intracranial conditions as well as those improving after corticosteroid treatment before the diagnosis were excluded. Ten cats met the inclusion criteria. The median duration of clinical signs was 7...

Why It Matters for Veterinary Professionals

For veterinary professionals, the practical value of this work lies in how the findings may support more structured clinical assessment, clearer monitoring, and more informed decisions for feline patients.

Practical Interpretation

The results should be interpreted in the context of the study design, population, inclusion criteria, and clinical setting. Application in practice should consider patient-specific risk factors, available diagnostics, local standards of care, and clinician judgment.

Clinical Takeaway

Overall, the study adds useful evidence for clinicians seeking to align daily practice with current veterinary research while maintaining a balanced, case-by-case approach.

Read the full article here.

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The combination of lomustine and corticosteroids is a valid chemotherapeutic option in cats with presumptive central nervous system lymphoma.

Clinical evidence update from Journal of the American Veterinary Medical Association

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