Assessment of Pancreatic Lipase Activity Using a Quantitative and a Qualitative Assay in Dogs with Chronic Kidney Disease.
Clinical evidence update from Animals : an open access journal from MDPI
Clinical Context
Peer-reviewed veterinary literature continues to shape everyday decision-making for canine patients, especially when new evidence clarifies diagnosis, treatment selection, monitoring, or clinical outcomes.
What the Study Evaluated
A study published in Animals : an open access journal from MDPI in 2026 evaluated assessment of Pancreatic Lipase Activity Using a Quantitative and a Qualitative Assay in Dogs with Chronic Kidney Disease..
Key Findings
Chronic kidney disease (CKD) in dogs is associated with increased serum pancreatic lipase activity, complicating the diagnosis of acute pancreatitis (AP). This prospective study evaluated pancreatic lipase activity measured using a quantitative DGGR assay in dogs with CKD while excluding cases with clinical or imaging evidence of AP, and the DGGR results were compared with the qualitative SNAP cPL test. Twenty-five dogs with IRIS stage 1-4 CKD were enrolled. The DGGR results were within the reference range in 52% of dogs and elevated in 48%, whereas the SNAP cPL results were abnormal in 72% of cases. Discordance between tests was common,...
Why It Matters for Veterinary Professionals
For veterinary professionals, the practical value of this work lies in how the findings may support more structured clinical assessment, clearer monitoring, and more informed decisions for canine patients.
Practical Interpretation
The results should be interpreted in the context of the study design, population, inclusion criteria, and clinical setting. Application in practice should consider patient-specific risk factors, available diagnostics, local standards of care, and clinician judgment.
Clinical Takeaway
Overall, the study adds useful evidence for clinicians seeking to align daily practice with current veterinary research while maintaining a balanced, case-by-case approach.
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