EXPRESS: Longitudinal comparison of serum pancreatic lipase activity and pancreatic lipase immunoreactivity with clinical signs in cats with suspicion of pancreatitis.
Clinical evidence update from Journal of feline medicine and surgery
Clinical Context
Peer-reviewed veterinary literature continues to shape everyday decision-making for feline patients, especially when new evidence clarifies diagnosis, treatment selection, monitoring, or clinical outcomes.
What the Study Evaluated
A study published in Journal of feline medicine and surgery in 2026 evaluated eXPRESS: Longitudinal comparison of serum pancreatic lipase activity and pancreatic lipase immunoreactivity with clinical signs in cats with suspicion of pancreatitis..
Key Findings
ObjectivesIt remains unclear whether pancreatic lipase immunoreactivity (PLI) and lipase activity similarly reflect clinical status and disease severity in cats with suspected pancreatitis. This retrospective cohort study aimed to directly compare their association with clinical disease severity over timeMethodsTwenty-one client-owned cats with suspicion of pancreatitis were followed up over a median of 6 weeks (range, 1-130). The median number of re-checks was 2 (range, 1-9). Lipase activity (LIPC Roche; RI, 8-26 U/L) and PLI (Spec fPL; RI, 0-4.4 µg/L ) were measured at each examination and compared to clinical status of cats expressed as a...
Why It Matters for Veterinary Professionals
For veterinary professionals, the practical value of this work lies in how the findings may support more structured clinical assessment, clearer monitoring, and more informed decisions for feline patients.
Practical Interpretation
The results should be interpreted in the context of the study design, population, inclusion criteria, and clinical setting. Application in practice should consider patient-specific risk factors, available diagnostics, local standards of care, and clinician judgment.
Clinical Takeaway
Overall, the study adds useful evidence for clinicians seeking to align daily practice with current veterinary research while maintaining a balanced, case-by-case approach.
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