Articles Companion animals

11 February 2026

Computed tomography in the diagnosis of canine hyperadrenocorticism not suppressible by dexamethasone

Computed tomography (ct) was performed in 10 dogs with hyperadrenocorticism not suppressible by dexamethasone. In 6 of these dogs, a unilateral adrenal mass was found on ct images.

Specimens of the masses were obtained via retroperitoneal laparotomy; histologic examination revealed 4 carcinomas, 1 adenoma, and 1 nodular hyperplasia. In the 4 other dogs, ct revealed symmetric bilateral adrenal gland enlargement.

In 2 of these dogs, contrast-enhanced ct revealed a mass in the pituitary fossa, which could be identified at necropsy as a pituitary tumor. The other 2 dogs were successfully treated with mitotane.

Authors: G. Voorhout, R. Stolp, A. A. M. E. Lubberink, P. E. G. M. van Waes

Source: https://avmajournals.avma.org/

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Computed tomography in the diagnosis of canine hyperadrenocorticism not suppressible by dexamethasone

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