Focal lipogranulomatous lymphangitis (FLL) is defined as a focal or regional inflammation of the lymphatic vessels and intestinal wall without a clear etiology. It is characterized by transmural granulomatous inflammation with lipogranulomas appearing as small white nodules of the intestinal wall or mesentery.
Although histological evaluation is required to definitively diagnose FLL, some reports have described the ultrasonographic features of FLL in dogs. However, to the best of the authors' knowledge, only 20 cases have been reported to date, and no studies have described the computed tomography (CT) features of FLL.
An eight-year-old Maltese dog presented with diarrhea and anorexia. Ultrasonography revealed marked focal wall thickening with loss of layering in the distal ileum.
Contrast-enhanced computed tomography (CT) revealed a preserved wall layer with hypoattenuating middle wall thickening. In some segments of the lesion, small nodules protruding toward the mesentery from the outer layer were observed. Histopathology revealed focal lipogranulomatous lymphangitis (FLL) with lymphangiectasia.
This is the first report to describe the CT features of FLL in a dog.
CT features of preserved wall layers with hypoattenuating middle wall thickening and small nodules can assist in diagnosing FLL in dogs.
Lee HW, Jung JW, Park S, Lee K, Lee SK. "Computed tomographic features of focal lipogranulomatous lymphangitis for differentiating from malignant intestinal lesions in a dog." J Vet Sci. 2023 Mar;24(2): e25. doi: 10.4142/jvs.22301. PMID: 37012033; PMCID: PMC10071275.
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