Articles Companion animals

25 June 2026

SGLT2 inhibitor therapy in diabetic cats: first clinical experiences with non-ideal candidates.

Clinical evidence update from Journal of feline medicine and surgery

Clinical Context

Peer-reviewed veterinary literature continues to shape everyday decision-making for feline patients, especially when new evidence clarifies diagnosis, treatment selection, monitoring, or clinical outcomes.

What the Study Evaluated

A study published in Journal of feline medicine and surgery in 2026 evaluated sGLT2 inhibitor therapy in diabetic cats: first clinical experiences with non-ideal candidates..

Key Findings

Case series summaryThis retrospective case series describes seven diabetic cats treated with velagliflozin that were considered non-ideal candidates for this therapy. These more complicated diabetic feline cases were referred to the Small Animal Department, Faculty of Veterinary Medicine, Ghent University, Belgium. The sole inclusion criterion for this case series was treatment with velagliflozin (Senvelgo; Boehringer Ingelheim) after diagnosis of diabetes mellitus. Data on signalment, medical history, clinical findings, diagnostics, treatment, response and outcomes were available for all cats. The initial consultation for all cats took...

Why It Matters for Veterinary Professionals

For veterinary professionals, the practical value of this work lies in how the findings may support more structured clinical assessment, clearer monitoring, and more informed decisions for feline patients.

Practical Interpretation

The results should be interpreted in the context of the study design, population, inclusion criteria, and clinical setting. Application in practice should consider patient-specific risk factors, available diagnostics, local standards of care, and clinician judgment.

Clinical Takeaway

Overall, the study adds useful evidence for clinicians seeking to align daily practice with current veterinary research while maintaining a balanced, case-by-case approach.

Read the full article here.

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SGLT2 inhibitor therapy in diabetic cats: first clinical experiences with non-ideal candidates.

Clinical evidence update from Journal of feline medicine and surgery

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