Chronic Kidney Disease in Cats
New university findings highlight potential implications for dogs, cancer, and veterinary practice.
The purpose of the study is to assess whether administration of a probiotic changes the natural gut microbial flora (microbiome) of these cats, and influences markers of renal (kidney) health and phosphate homeostasis through this microflora change.
Chronic Kidney Disease in Cats | College of Veterinary Medicine at MSU Support the College of Veterinary Medicine Search Tool Clinical Trials Select CHOP VS.
This project wishes to recruit cats that have CKD, IRIS Stage 2-4.
We will be assessing the microbiome, and effect of a probiotic on CKD status, in particular calcium/phosphate metabolism.
The study is a blinded (owner) cross-over prospective trial.
Inclusion Criteria: Must be either voluntarily eating, or being fed through a feeding tube, a renal therapeutic diet for the past 6 weeks (no specific diet brand or stage required) up to 80-90% total daily caloric intake.
Owners willing to commit to supplementing their cat a probiotic (or placebo product) for two 8-week periods, maintain current diet, keep a home diary of clinical status, collect and post a stool sample from their cat 3 times (at no cost) and to visit the MSU Veterinary Medical Center for 4 visits.
Must be current on parasite (endo- and ecto-) control.
Confirmation of CKD status within past 3 months.
Exclusion Criteria: Other systemic illness (please note not all are excluded; please check if uncertain).
Evidence of acute or acute-on-chronic kidney disease.
The report adds to ongoing university-led research relevant to veterinary medicine, animal health, and clinical decision-making.
Source university website: Michigan State University College of Veterinary Medicine
https://cvm.msu.edu/hospital/veterinarians/clinical-trials/chronic-kidney-disease-in-cats
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