Point-of-care (POC) glucometry is commonly used in horses; however, measurement error with this method when analysing hypoglycaemic samples (<4mmol/L) is unknown. The objective of this study was to determine the precision and accuracy of glucometry in hypoglycaemic horses in comparison to a laboratory method of glucose measurement (LAB).
Repeatability coefficients were 0.47mmol/L for POC and 0.09mmol/L for LAB, and coefficients of variation were 10% and 2.11%, for the POC and LAB methods, respectively. Systemic bias with the POC method was present, with a mean bias of -0.26mmol/L (95% limits of agreement: -0.88 - 0.37) in comparison to LAB, and <70% of measurements were within 20% of paired LAB results.
The findings of this study indicate that the precision/repeatability of the glucometer was likely adequate for clinical use in hypoglycaemic horses. However, underestimation of glucose concentrations precludes interchangeable use of POC measurements with results from reference methods. Prior to use of glucometers, assessment of the diagnostic performance of the equipment is necessary, including determination of acceptable criteria and reference ranges for hypoglycaemic samples.
“Precision and accuracy of a point of care glucometer for detection of hypoglycaemia in horses”. Kristopher Hughes, et al. Vet J. 2024 Apr 8:106109. doi: 10.1016/j.tvjl.2024.106109.
Source: https://www.sciencedirect.com/science/article/pii/S1090023324000480
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