Articles Companion animals

16 February 2023

Neurosurgery in feline epilepsy

Feline epilepsy is treated with antiseizure medications, which achieves fair to good seizure control. However, a small subset of feline patients with drug-resistant epilepsy requires alternative therapies.

Approximately 50% of cats with epileptic seizures are diagnosed with structural epilepsy with or without hippocampal abnormality and may respond to surgical intervention. The presence of hippocampal pathology and intracranial tumors is a key point to consider for surgical treatment.

The authors of this review described feline epilepsy syndrome and epilepsy-related pathology, and discussed the indications for and availability of neurosurgery, including lesionectomy, temporal lobectomy with hippocampectomy, and corpus callosotomy, for cats with different epilepsy types.

Highlights from the study include that:

There are some ‘epilepsy syndromes’ in feline epilepsy.
Hippocampal lesion such as sclerosis or necrosis is a key of feline epilepsy.
Brain tumors, especially meningiomas, often cause structural epilepsy in cats.
Cortical resection or lesionectomy needs electroencephalographic evidence.
Temporal lobectomy with hippocampectomy and corpus callosotomy are available.

Daisuke Hasegawa et al. “Neurosurgery in feline epilepsy, including clinicopathology of feline epilepsy syndromes.” Vet J. 2022 Dec; 290:105928. doi: 10.1016/j.tvjl.2022.105928.

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