MY ACCOUNT | NEWSLETTER |

Investigating Salmonella Nervous System Infection in Chickens

The animals exhibited neurological symptoms and the isolates from brain tissue contained two virulent genes.


Salmonella infections are a frequent cause of systemic pathologies in poultry production. This also includes the nervous system, the impact of which has hardly been studied.

Therefore, a study was carried out that aimed to detect an alternative pathogenic pathway in the invasion of brain tissue in chickens by Salmonella spp. Brain infection produces neurological symptoms and Salmonella strains isolated from brain tissue showed the presence of two virulent genes. Verification of the route from the intestinal mucosa through the blood-brain barrier was achieved by experimental infections in day-old chicks free of specific pathogens, through two routes of inoculation.

Salmonella spp. of five flocks of chickens showing central nervous system symptoms by serotyping and antimicrobial testing. Virulence profiles were described using the detection of the virulence plasmid spvC and the Salmonella plasmid sopB. A pathogenicity study of isolates in day-old chickens free of specific pathogens by oral and intracerebral administration was carried out, and experimental infection in embryonated chicken eggs free of specific pathogens by intra-vitelline and intra-allantoic administration was investigated. Histopathology and immunohistopathology against Salmonella antigen were also performed in brain tissue.

Three isolated serotypes

Three Salmonella serotypes were isolated from the brains of five batches: two from Salmonella Virchow, two from Salmonella Kentucky, and one from Salmonella Enteritidis. The sopB gene and the spvC plasmid-mediated operon were identified in all isolated strains. Salmonella strains were re-isolated and identified in the brain and internal organs of post-experimental infected chickens. The infected chicks showed nervous symptoms associated with Salmonella infection. The presence of Salmonella antigens in the staining of brain tissues also indicates penetration of the blood-brain barrier.

In conclusion, the results of this study indicate that some virulent systemic strains of Salmonella spp. can induce symptoms in the central nervous system of affected chickens.

Heba Badr, Mohamed A. Soliman and Soad A. Nasef. Bacteriological and molecular study of Salmonella species associated with central nervous system manifestation in chicken flocks. Veterinary World, 13(10): 2183-2190. doi: www.doi.org/10.14202/vetworld.2020.2183-2190 

Like0
Dislike0
  • Please enter a comment


Name *
Email address *
Comment *


* Required fields

Information on the processing of your personal data
We inform you that, in compliance with the provisions of current national and European regulations for the Protection of Personal Data and Services of the Information Society and Electronic Commerce, by sending us this form you are expressly giving your consent to Grupo Asís Biomedia , SL, (hereinafter, "ASIS GROUP") so that, as the person in charge, it may process your personal data in order to respond to your request for contact and information by electronic means.

Likewise, when you expressly consent, we will process your personal data to send you specialized information, newsletters, offers and exclusive promotions from GRUPO ASIS and related companies.

For the aforementioned purpose, GRUPO ASIS may transfer your data to other companies linked to GRUPO ASIS or to third party service providers for the management of electronic communications and other security services, even in cases where they are outside of the European Union, provided that they legally guarantee the adequate level of protection required by European regulations.

At any time you can withdraw the consent given and exercise the rights of access, rectification, deletion, portability of your data and limitation or opposition to its treatment by contacting GRUPO ASIS by sending an email to protecciondatos @ grupoasis.com, or by written communication to address at Centro Empresarial El Trovador, 8th floor, office I, Plaza Antonio Beltrán Martínez 1, 50002, Zaragoza (Spain), indicating in either case the Ref. Personal data and the right you exercise, as well as attaching a copy of your ID or replacement identification document.


I have read and accept the treatment of my data according to the informed purpose and according Legal notes and the Privacy Policy
I wish to receive commercial information from GRUPO ASIS and related companies



More news

WVC Annual Conference 2024

Like0
Dislike0

Diagnostic accuracy of plain radiography to identify synovial penetration in horses with traumatic limb wounds

Like0
Dislike0

Effects of administration of vitamin C on oxidative status in healthy horses

Like0
Dislike0

Viticus Group 96th WVC Annual Conference is Back – It’s Time to Vet Differently

Like0
Dislike0

Exocrine pancreatic insufficiency in dogs and cats

Like0
Dislike0

Newsletter

 
 

News of interest

EVENTS

Copyright © 2024 - All Rights Reserved
ISSN 2768-198X

Top