Evaluation of oxidative stress and antioxidant defense biomarkers in healthy and colic horses: correlation with type of colic and outcome.
Clinical evidence update from Journal of veterinary internal medicine
Clinical Context
Peer-reviewed veterinary literature continues to shape everyday decision-making for production animal practice, especially when new evidence clarifies diagnosis, treatment selection, monitoring, or clinical outcomes.
What the Study Evaluated
A study published in Journal of veterinary internal medicine in 2026 evaluated evaluation of oxidative stress and antioxidant defense biomarkers in healthy and colic horses: correlation with type of colic and outcome..
Key Findings
Colic is a major cause of morbidity and mortality in horses, with oxidative stress implicated in its pathophysiology. Evaluate biomarkers (BIOs) of oxidative stress and antioxidant defense in healthy horses and those with non-strangulating colic (NSC) and strangulating colic (SC) and assess correlations with survival. Seventy-one adult horses: 10 healthy and 61 colic-affected (42 NSC, 19 SC) admitted to 3 veterinary teaching hospitals. Prospective, multicenter cohort study. Blood samples were collected at admission (T0) and up to 96 h post-admission. Biomarkers measured included arylesterase (AREase), paraoxonase (POase), lipid peroxidation...
Why It Matters for Veterinary Professionals
For veterinary professionals, the practical value of this work lies in how the findings may support more structured clinical assessment, clearer monitoring, and more informed decisions for production animal practice.
Practical Interpretation
The results should be interpreted in the context of the study design, population, inclusion criteria, and clinical setting. Application in practice should consider patient-specific risk factors, available diagnostics, local standards of care, and clinician judgment.
Clinical Takeaway
Overall, the study adds useful evidence for clinicians seeking to align daily practice with current veterinary research while maintaining a balanced, case-by-case approach.
Read the full article here.
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